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  • Jun. 19th, 2009 at 1:15 PM

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  • Apr. 28th, 2009 at 10:33 AM

Generic player Watson Pharma confirmed (in a press release Here) that it has filed Abbreviated New Drug Applications (ANDA) with Paragraph IV certification on Dextromethorphan HBr+ Guaifenesin 30 mg+600 mg and 60 mg+1200 mg ER tablets. Watson has challenged innovator Reckitt Benckiser following Orange Book listed patents on Dextromethorphan HBr+ Guaifenesin ER 30 mg+600 mg and 60 mg+1200 mg tablets (Mucinex):

US6372252 (Assignee: Adams Lab): Which covers a modified release tablet having two portions, wherein a first portion comprises a first quantity of guaifenesin in an immediate release form which becomes fully bioavailable in the subject's stomach and a second portion comprises a second quantity of guaifenesin and a release-delaying matrix comprising a hydrophilic polymer and a water-insoluble polymer wherein the weight ratio of said hydrophilic polymer to said water-insoluble polymer is in the range of from about 1:1 to about 6.8:1, wherein said tablet demonstrates a Cmax in a human subject equivalent to the Cmax obtained when the first of three doses of a standard immediate release formulation having one third the amount of guaifenesin is dosed every four hours over a 12 hour period, and wherein said tablet also provides therapeutically effective bioavailability for at least twelve hours after a single dose in a human subject according to serum analysis.
US6955821 (Assignee: Adams Lab): Which covers a modified release drug product comprising a first quantity of guaifenesin in an immediate release formulation wherein the guaifenesin becomes bioavailable in a subject's stomach; a second quantity of guaifenesin in a release-delaying matrix; and at least one additional drug, wherein the release-delaying matrix comprises a hydrophilic polymer and a water-insoluble polymer in a weight ratio of hydrophilic polymer to water-insoluble polymer from about 1:1 to about 9:1, wherein the immediate release formulation guaifenesin has a Cmax in a human subject equivalent to the Cmax obtained when a dose of a standard immediate release formulation having one third the amount of guaifenesin is dosed, and immediately after administration the serum concentration of guaifenesin peaks in about an hour, followed by a gradual serum concentration decrease over twenty-four hours but the serum concentration of guaifenesin never decreases below the minimum concentration of said standard immediate release formulation over twelve hours, and wherein the drug product releases a therapeutically effective bioavailable guaifenesin dose for at least twelve hours after a single dose in the human subject according to serum analysis.

Innovator Reckitt Benckiser has filed suit against Watson on April 20, 2009 in the U.S. District Court for the Southern District of New York seeking to prevent Watson from commercializing its products prior to expiration of 821 and 252 patents

Dextromethorphan HBr+ Guaifenesin ER tablets are indicated to help loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive.

According to IMS Health data for the twelve-months ended December 31, 2008, Dextromethorphan HBr+ Guaifenesin ER tablets 30 mg+600 mg and 60 mg+1200 had total U.S. sales of approximately $106 million and $85 million respectively,.

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  • Apr. 26th, 2009 at 3:54 PM

Generic player Watson Pharma confirmed (in a press release Here) that it has filed Abbreviated New Drug Applications (ANDA) with Paragraph IV certification on Dextromethorphan HBr+ Guaifenesin 30 mg+600 mg and 60 mg+1200 mg ER tablets. Watson has challenged innovator Reckitt Benckiser following Orange Book listed patents on Dextromethorphan HBr+ Guaifenesin ER 30 mg+600 mg and 60 mg+1200 mg tablets (Mucinex):

US6372252 (Assignee: Adams Lab): Which covers a modified release tablet having two portions, wherein a first portion comprises a first quantity of guaifenesin in an immediate release form which becomes fully bioavailable in the subject's stomach and a second portion comprises a second quantity of guaifenesin and a release-delaying matrix comprising a hydrophilic polymer and a water-insoluble polymer wherein the weight ratio of said hydrophilic polymer to said water-insoluble polymer is in the range of from about 1:1 to about 6.8:1, wherein said tablet demonstrates a Cmax in a human subject equivalent to the Cmax obtained when the first of three doses of a standard immediate release formulation having one third the amount of guaifenesin is dosed every four hours over a 12 hour period, and wherein said tablet also provides therapeutically effective bioavailability for at least twelve hours after a single dose in a human subject according to serum analysis.
US6955821 (Assignee: Adams Lab): Which covers a modified release drug product comprising a first quantity of guaifenesin in an immediate release formulation wherein the guaifenesin becomes bioavailable in a subject's stomach; a second quantity of guaifenesin in a release-delaying matrix; and at least one additional drug, wherein the release-delaying matrix comprises a hydrophilic polymer and a water-insoluble polymer in a weight ratio of hydrophilic polymer to water-insoluble polymer from about 1:1 to about 9:1, wherein the immediate release formulation guaifenesin has a Cmax in a human subject equivalent to the Cmax obtained when a dose of a standard immediate release formulation having one third the amount of guaifenesin is dosed, and immediately after administration the serum concentration of guaifenesin peaks in about an hour, followed by a gradual serum concentration decrease over twenty-four hours but the serum concentration of guaifenesin never decreases below the minimum concentration of said standard immediate release formulation over twelve hours, and wherein the drug product releases a therapeutically effective bioavailable guaifenesin dose for at least twelve hours after a single dose in the human subject according to serum analysis.

Innovator Reckitt Benckiser has filed suit against Watson on April 20, 2009 in the U.S. District Court for the Southern District of New York seeking to prevent Watson from commercializing its products prior to expiration of 821 and 252 patents

Dextromethorphan HBr+ Guaifenesin ER tablets are indicated to help loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive.

According to IMS Health data for the twelve-months ended December 31, 2008, Dextromethorphan HBr+ Guaifenesin ER tablets 30 mg+600 mg and 60 mg+1200 had total U.S. sales of approximately $106 million and $85 million respectively,.

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  • Apr. 14th, 2009 at 1:49 PM

I wanted you to know that we have used your CanTravel granules for my little girl with great success. CanTravel is wonderful because it works so well and is amazingly easy to give to children
Fiona J.
Motion makes the world go round
In sickness and in health, we all have to travel sometime. Whether it is a business trip or a vacation, people these days travel all over the world, up and down in cars, planes and boats people are always on the move! While some love to travel, others are home bodies preferring not to be in motion, but to remain with their feet firmly on the ground! Even little children, who normally love to be in motion, can sometimes get sick and tired of traveling!
Being able to maintain digestive harmony and comfort while traveling can make your journeys pleasant and enjoyable.
The natural way
Before going on a journey, make sure that you do not eat rich foods and that you avoid overloading your digestive system. Traveling light is relevant to your stomach as well as your suitcase! Children should also not be given candy and other junk food while traveling. An apple or banana would be far more comfortable for their digestive systems!
If your journey is a long one and includes a meal, avoid heavy, difficult-to-digest foods and rather have fruit and salads. Munch on a dry cracker to prevent excess saliva in the mouth and even suck on a mint to keep your mouth and digestive system feeling fresh. Also make sure that you are dressed comfortably without any tight belts or uncomfortable necklines. Loose, cotton clothing helps you to feel relaxed and that can contribute to digestive comfort as well.
Natural remedies have been used for generations to support digestive health during traveling and can be very useful to take along with you when you are going on a trip.
What is CanTravel?
CanTravel is a unique formula containing a combination of selected herb and biochemic tissue salts to support harmony and digestive comfort during traveling. Whether your journey is by air, sea, or road, CanTravel is a traveling partner that will be with you all the way to make your trip a pleasure and help you to enjoy traveling like never before!
Presented in pleasant and fresh-tasting dissolvable granules that are sprinkled on the tongue, CanTravel is easy and convenient to administer to adults and small children alike.
How has CanTravel helped others?
I wanted you to know that we have used your CanTravel granules for my little girl with great success. CanTravel is wonderful because it works so well and is amazingly easy to give to children. Just a sprinkle on the tongue and she is a happy chappy again and she loves the taste! I can highly recommend this product.Fiona J.
Thank you for a very successful treatment . I can recommend this remedy to anyone because it has really worked for me! What a pleasure to be able to go on a boat trip with my friends for the first time!!!!!!!!As a mother, I really cant believe that I have finally found a solution for my son! (10 years old) These granules are tasty - after some initial refusal, he now loves taking them and they work so well. His father and I were amazed at how we could all sing along in the car the other day (including him!) It is also a great relief that he can accompany his class on school outings. Thank you for recommending this product to me!Jess (grateful mother)
Hello, I race cars. I decided to try the natural remedy. I really was so surprised how well this works. It tastes good, too! A capful before a race and every other hour thereafter truly made a difference. My race buddies have also started to use this product. It really does work very well. Thanks. SincerelyBlake, CA
Ready to Purchase.

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  • Apr. 12th, 2009 at 1:39 AM

I wanted you to know that we have used your CanTravel granules for my little girl with great success. CanTravel is wonderful because it works so well and is amazingly easy to give to children
Fiona J.
Motion makes the world go round
In sickness and in health, we all have to travel sometime. Whether it is a business trip or a vacation, people these days travel all over the world, up and down in cars, planes and boats people are always on the move! While some love to travel, others are home bodies preferring not to be in motion, but to remain with their feet firmly on the ground! Even little children, who normally love to be in motion, can sometimes get sick and tired of traveling!
Being able to maintain digestive harmony and comfort while traveling can make your journeys pleasant and enjoyable.
The natural way
Before going on a journey, make sure that you do not eat rich foods and that you avoid overloading your digestive system. Traveling light is relevant to your stomach as well as your suitcase! Children should also not be given candy and other junk food while traveling. An apple or banana would be far more comfortable for their digestive systems!
If your journey is a long one and includes a meal, avoid heavy, difficult-to-digest foods and rather have fruit and salads. Munch on a dry cracker to prevent excess saliva in the mouth and even suck on a mint to keep your mouth and digestive system feeling fresh. Also make sure that you are dressed comfortably without any tight belts or uncomfortable necklines. Loose, cotton clothing helps you to feel relaxed and that can contribute to digestive comfort as well.
Natural remedies have been used for generations to support digestive health during traveling and can be very useful to take along with you when you are going on a trip.
What is CanTravel?
CanTravel is a unique formula containing a combination of selected herb and biochemic tissue salts to support harmony and digestive comfort during traveling. Whether your journey is by air, sea, or road, CanTravel is a traveling partner that will be with you all the way to make your trip a pleasure and help you to enjoy traveling like never before!
Presented in pleasant and fresh-tasting dissolvable granules that are sprinkled on the tongue, CanTravel is easy and convenient to administer to adults and small children alike.
How has CanTravel helped others?
I wanted you to know that we have used your CanTravel granules for my little girl with great success. CanTravel is wonderful because it works so well and is amazingly easy to give to children. Just a sprinkle on the tongue and she is a happy chappy again and she loves the taste! I can highly recommend this product.Fiona J.
Thank you for a very successful treatment . I can recommend this remedy to anyone because it has really worked for me! What a pleasure to be able to go on a boat trip with my friends for the first time!!!!!!!!As a mother, I really cant believe that I have finally found a solution for my son! (10 years old) These granules are tasty - after some initial refusal, he now loves taking them and they work so well. His father and I were amazed at how we could all sing along in the car the other day (including him!) It is also a great relief that he can accompany his class on school outings. Thank you for recommending this product to me!Jess (grateful mother)
Hello, I race cars. I decided to try the natural remedy. I really was so surprised how well this works. It tastes good, too! A capful before a race and every other hour thereafter truly made a difference. My race buddies have also started to use this product. It really does work very well. Thanks. SincerelyBlake, CA
Ready to Purchase.

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?

  • Dec. 9th, 2008 at 9:16 PM

Heart Will Go On, Celine Dion. This was very easy to get sick of as well; cloying and over-the-top and insisting on its own epic greatness. Blurg. The music's pretty; I have a string quartet version that didn't make it onto the soundtrack (from a promo CD) that's lovely. It doesn't need Celine Dion or lyrics to work. It sounds better without them.
My Favorite Nominee: Ray of Light, Madonna. I don't have much to say about it, but it works.
My Favorite Single That Year: Flagpole Sitta, Harvey Danger. That song just makes me feel awesome. I love it.

1998
Winner: Sunny Came Home, Shawn Colvin. Music from the nineties has an overwhelming percentage of suck, more than any decade. It's like America went through menopause and could only listen to this kind of sappy pap. I hate this thing, and thanks to the Crap and Crap Lite stations being played where I worked constantly, I heard it way too many fucking times.
My Favorite Nominee: MMMBop, Hanson. It's a default choice; it's the one I think is okay whereas I despise all the others (especially "Where Have All the Cowboys Gone" by Paul Cole, which should be classified a form of abuse).
My Favorite Single That Year: The End Is the Beginning Is the End, Smashing Pumpkins. I love that they used it in the Watchmen trailer.

1997
Winner: Change the World, Eric Clapton. I'm not much of a Clapton fan, really. I did like this song, although it's association with the awful Scientology-promoting John Travolta film Phenomenon counts against it a tad. It's not earth-shaking, but it's a solid, not-unpleasant song.
My Favorite Nominee: 1979, Smashing Pumpkins. Haunting, beautiful, and bittersweet.
My Favorite Single That Year: 1979, Smashing Pumpkins.

1996
Winner: Kiss from a Rose, Seal. I think it's a beautiful song. I used to hear it a lot on the radio as I was driving to work in the winter at a very dark 5 in the morning. That's the perfect time to hear it. It'll take you on a trip.
My Favorite Nominee: Kiss from a Rose, Seal.
My Favorite Single That Year: Kiss from a Rose, Seal.

1995
Winner: All I Wanna Do, Sheryl Crow. Blurg. Not a song I like.
My Favorite Nominee: Streets of Philadelphia, Bruce Springsteen. Beautiful, sad, and seething with quiet ange, disappointment, and acceptance of fear.
My Favorite Single That Year: Streets of Philadelphia, Bruce Springsteen.

1994
Winner: I Will Always Love You, Whitney Houston. Piece of overplayed shit. Especially in comparison to the original Dolly Parton song, which is perfect.
My Favorite Nominee: The River of Dreams, Billy Joel.
My Favorite Single That Year: Fields of Gold, Sting. Kind of a cheesy choice, perhaps, but I can always hear it and always love it. It's simple and pretty.

1993
Winner: Tears in Heaven, Eric Clapton. It doesn't quite hold up for me, honestly, but it's miles better than fellow nominee "Achy Breaky Heart." It's a very pretty song, but not my favorite of Clapton's.
My Favorite Nominee: Constant Craving, k.d. lang. I like the passion.
My Favorite Single That Year: One, U2. One of the most achingly beautiful songs I've ever heard.

1992
Winner: Unforgettable, Natalie Cole. The fact that the Grammys honored that hacky, schlocky, sympathy-begging, cloying bit of grave-robbing Natalie Cole did to cash in on honor her father is as sad as it is unsurprising.
My Favorite Nominee: Losing My Religion, R.E.M. It was overplayed, but if you listen to it now, it sounds almost fresh again. It really is just a good song.
My Favorite Single That Year: Crazy, Seal.

1991
Winner: Another Day in Paradise, Phil Collins. Preachy, annoying, and not even the best song from that Phil Collins album. (Actually, I just checked and sadly, it is. I despise "Something Happened on the Way to Heaven," and "I Wish It Would Rain" just sounds like a rip-off of "Wish You Were Here" with Clapton on guitar.)
My Favorite Nominee: Nothing Compares 2 U, Sinead O'Connor. Of the sappy, preachy, sad sack songs that were nominated this year, this is the one that's actually a good song. (Also, "U Can't Touch This" was nominated this year, but come on, man.)
My Favorite Single This Year: Enjoy the Silence, Depeche Mode. Now there's a love song.

1990
Winner: Wind Beneath My Wings, Bette Midler. I hate this song, and my dad pissed me off by playing it at his wedding reception for his mother, which I specifically told him not to do because it was such a fucking cliche. He said he wouldn't; he did. Wow, my grandma must have been one of 10 million special woman so uniquely honored that year. It's the equivalent of buying your dad a tie on Father's Day.
My Favorite Nominee: The End of the Innocence, Don Henley. Chance is right on when he calls it deceptively angry. It adds some world-weariness on top of that, too. Beautiful song.
My Favorite Single That Year: A Little Respect, Erasure. I usually come out on the side of pop, I guess. Although besides the catchiness, I think the lyrics are beautiful. One of my all time favorite lyrics comes from this song: "What religion or reason could drive a man to forsake his lover?"

1989
Winner: Don't Worry, Be Happy, Bobby McFerrin. I always liked this song, but it sure wasn't the best of the year. I think part of it was the novelty of McFerrin doing the whole thing a cappella. Which is admittedly neat.
My Favorite Nominee: Don't Worry, Be Happy, Bobby McFerrin.
My Favorite Single That Year: Sweet Child O' Mine, Guns 'n' Roses. The most perfect song they ever recorded.

1988
Winner: Graceland, Paul Simon. I'm not a big fan of this song for whatever reason. It's nice, but it's okay. I wouldn't turn it off if it came on the radio station. Really, I just don't dig Paul Simon's solo work that much.
My Favorite Nominee: Back in the High Life Again, Steve Winwood. Admittedly, mostly because it reminds me of better times. But it's pretty.
My Favorite Single That Year: With or Without You, U2. Grammy nominated the more ubiquitous and much less beautiful "I Still Haven't Found What I'm Looking For," a song I don't like. "With or Without You" is real passion.

1987
Winner: Higher Love, Steve Winwood. Meh. It's okay.
My Favorite Nominee: Sledgehammer, Peter Gabriel. It's a lot of sucky nominees this year, but this is a great song.
My Favorite Single That Year: True Colors, Cyndi Lauper. A beautiful love song, especially for people who don't feel so great about themselves. I guess I like genuine songs about understanding, I would say.

1986
Winner: We Are the World, USA for Africa. Of course. Nothing else was going to win this year. As a song, it's okay. The real fun is trying to pick out all the singers. I mean, you know, it's Really Important, but it's just okay.
My Favorite Nominee: Money for Nothing, Dire Straits. One of their couple of songs I like. One of my favorite guitar solos.
My Favorite Single That Year: Take on Me, a-Ha. Pop perfection in all of its catchy, bubblegum glory.

1985
Winner: What's Love Got to Do with It, Tina Turner. There's genuine force behind it (although I think "Private Dancer" is her best song), real heartbreak.
My Favorite Nominee: Dancing in the Dark, Bruce Springsteen. At his most pop. I love this song.
My Favorite Song That Year: Time After Time, Cyndi Lauper. Gorgeous and simple.

1984
Winner: Beat It, Michael Jackson. Not much of a surprise, I guess. And it's a good song. Eddie Van Halen's guitar solo alone...
My Favorite Nominee: Flashdance... What a Feeling, Irene Cara. All of the nominees this year are pretty good but nothing I feel especially attached to. This is one of those cheesy pop songs I like.
My Favorite Single That Year: Our House, Madness. One of the most perfect songs I've ever loved.

1983
Winner: Rosanna, Toto. It's okay.
My Favorite Nominee: Steppin' Out, Joe Jackson. That one always got me and carried me off.
My Favorite Single That Year: Under Pressure, Queen David Bowie. Everything that's shitty about society in four and a half minutes. "And love dares you to care for the people on the edge of the night."

1982
Winner: Bette Davis Eyes, Kim Carnes. Meh. I don't feel strongly either way.
My Favorite Nominee: (Just Like) Starting Over, John Lennon. What a great song. I can't believe it lost to Kim Carnes... greatness versus... well, nothing worth commenting on. As usual, John Lennon just nails life and relationships with this song.
My Favorite Single This Year: In the Air Tonight, Phil Collins. Collins used to be a man who just knew darkness and how it felt to be depressed and angry.

1981
Winner: Sailing, Christopher Cross. Put me to sleep, why don't ya?
My Favorite Nominee: Theme from New York, New York, Frank Sinatra.
My Favorite Single That Year: Let My Love Open the Door, Pete Townshend. As great a song as he ever wrote for the Who, his best solo work, and one of his most genuinely passionate songs.

1980
Winner: What a Fool Believes, the Doobie Brothers. I'm not a fan of theirs. This is probably the one song of theirs I'd say I liked. Still, Record of the Year? Feh.
My Favorite Nominee: I Will Survive, Gloria Gaynor. I like the sweep of it.
My Favorite Single That Year: Video Killed the Radio Star, the Buggles. Another perfect pop record.

1979
Winner: Just the Way You Are, Billy Joel. It is a pretty song, however much Joel claims now that he wrote it accidentally. Is he ever going to stop apologizing for having good commercial instincts? One of his less angry songs, too. I've always liked it.
My Favorite Nominee: Baker Street, Gerry Rafferty. Or as I always used to call it, "That One with the Great Saxophone Part."
My Favorite Single That Year: Who Are You, the Who. My favorite song of theirs, for reasons I can't quite define. But it's a great damn song.

1978
Winner: Hotel California, the Eagles. I hate the Eagles, but I'll give them this one song. This is a damn good song.
My Favorite Nominee: Hotel California, the Eagles.
My Favorite Single That Year: Hotel California, the Eagles.

1977
Winner: This Masquerade, George Benson. I couldn't tell you how this goes.
My Favorite Nominee: Afternoon Delight, Starland Vocal Band. It's delightful.
My Favorite Single That Year: Somebody to Love, Queen. A beautiful epic of emotion. One of my favorite songs ever.

1976
Winner: Love Will Keep Us Together, the Captain Tennille. It's okay.
My Favorite Nominee: At Seventeen, Janis Ian.
My Favorite Single That Year: Young Americans, David Bowie. That one packs a wallop and makes "Love Will Keep Us Together" sound pretty frivolous.

1975
Winner: I Honestly Love You, Olivia Newton-John. I honestly detest this cloying, overwrought song.
My Favorite Nominee: Don't Let the Sun Go Down on Me, Elton John. You want passion? There you go. Skip the other song entirely.
My Favorite Single That Year: Cat's in the Cradle, Harry Chapin. Hey, hey, it's a cliched choice for a reason.

1974
Winner: Killing Me Softly with His Song, Roberta Flack. It's pretty. It's also soporific.
My Favorite Nominee: You're So Vain, Carly Simon. A nice kiss-off song.
My Favorite Single That Year: Mind Games, John Lennon. Gorgeous.

1973
Winner: The First Time Ever I Saw Your Face, Roberta Flack. I've always found this song kind of overwrought.
My Favorite Nominee: American Pie, Don McLean. Come on, how could you pick a different one? (Although I've always loved Gilbert O'Sullivan's "Alone Again (Naturally)," a deceptively bleak and saddening song.)
My Favorite Single That Year: Let's Stay Together, Al Green. You want to get laid? You need some Al Green music.

1972
Winner: It's Too Late, Carole King. I can't place it off the top of my head, but I've never liked Carole King's as a singer.
My Favorite Nominee: My Sweet Lord, George Harrison. It's not much of a song, really, but I didn't like any of the other nominees much.
My Favorite Single That Year: Imagine, John Lennon. I can't believe this was never nominated for Record of the Year. What the hell?

1971
Winner: Bridge Over Troubled Water, Simon and Garfunkel. An undeniably beautiful song.
My Favorite Nominee: Let It Be, the Beatles. Still Paul McCartney's most beautiful effort.
My Favorite Single That Year: Let It Be, the Beatles. Seriously, they didn't pick this?

1970
Winner: Aquarius/Let the Sunshine In, the Fifth Dimension. Definitely a good song.
My Favorite Nominee: A Boy Named Sue, Johnny Cash. It's funny and Cash delivers it well. I'll always pull for Shel Silverstein.
My Favorite Single That Year: Suspicious Minds, Elvis Presley. His final masterpiece, one of his best songs (in my top five).

1969
Winner: Mrs. Robinson, Simon and Garfunkel. Good but not really special.
My Favorite Nominee: Hey Jude, the Beatles. A masterpiece.
My Favorite Single That Year: (Sittin' on) The Dock of the Bay, Otis Redding. One of the most quietly perfect songs I've ever heard.

1968
Winner: Up, Up and Away, the Fifth Dimension. What a lame choice. I mean, it's a cute song, but what a lame choice at this point in music history.
My Favorite Nominee: My Cup Runneth Over, Ed Ames.
My Favorite Single That Year: Can't Take My Eyes Off You, Frankie Valli. But that's the tip of the iceberg; this year produced, off the top of my head, "Heroes and Villains," "All You Need Is Love," "I Was Made to Love Her," "Light My Fire," "A Whiter Shade of Pale," and "(You Make Me Feel Like a) Natural Woman," and Grammy nominates "Ode to Billie Joe"? Lame, lame, lame.

1967
Winner: Strangers in the Night, Frank Sinatra. A good song, one I always liked.
My Favorite Nominee: Strangers in the Night, Frank Sinatra.
My Favorite Single That Year: Good Vibrations, the Beach Boys. Another incredible year for rock, and the Grammys can only acknowledge "Monday, Monday." What a foolish institution to pass over the greatness they did.

1966
Winner: A Taste of Honey, Herb Alpert and the Tijuana Brass. The best of the several thousand versions that seem to be out there.
My Favorite Nominee: Yesterday, the Beatles. As beautiful a song as was ever written.
My Favorite Single That Year: Like a Rolling Stone, Bob Dylan. Transcendent.

1965
Winner: The Girl from Ipanema, Stan Getz João Gilberto. A lovely little song that I've always liked as background music.
My Favorite Nominee: Downtown, Petula Clark. I forget just how beautiful this one is.
My Favorite Single That Year: Don't Worry, Baby, the Beach Boys. Perfect.

1964
Winner: Days of Wine and Roses, Henry Mancini. Nothing song from a rather turgid movie.
My Favorite Nominee: Dominique, the Singing Nun. That's painful to say, but the nominees this year are just that bad. Again, zero acknowledgement of rock and roll or even the great folk music from this time.
My Favorite Single That Year: Surfer Girl, the Beach Boys. Hey, Brian Wilson just knows how to hit me where it counts. Teenage love deified.

1963
Winner: I Left My Heart in San Francisco, Tony Bennett. A beautiful song.
My Favorite Nominee: I Left My Heart in San Francisco, Tony Bennett.
My Favorite Single That Year: Telstar, the Tornados. That one always takes me right off and makes me love being alive.

1962
Winner: Moon River, Henry Mancini. I'm never sorry to have heard this song. It's always beautiful, and always necessary.
My Favorite Nominee: Moon River, Henry Mancini. Infinitesimal second: "Take Five" by Dave Brubeck.
My Favorite Single That Year: Stand by Me, Ben E. King. The best time to hear this song is in the still of the deep night.

1961
Winner: Theme from A Summer Place, Percy Faith. The music is pretty.
My Favorite Nominee: Georgia on My Mind, Ray Charles. It's insane that this didn't win. This is the very definition of a beautiful song.
My Favorite Single That Year: Georgia on My Mind, Ray Charles.

1960
Winner: Mack the Knife, Bobby Darin. I like this song; it's fun as hell to sing along to.
My Favorite Nominee: Mack the Knife, Bobby Darin.
My Favorite Single That Year: Sleepwalk, Santo Johnny. Another great late night song.

1959
Winner: Nel Blu Dipinto Di Blu (Volare), Domenico Modugno. Okay. I can't believe anyone does this song better than Dean Martin, personally. I don't believe I've heard this version.
My Favorite Nominee: The Chipmunk Song (Christmas Don't Be Late), David Seville. I know, I know, but I love this song. It's a Christmas staple to me. It reminds me of being a kid and spending the lead-up to Christmas at my grandmother's house. It's a cozy song for me.
My Favorite Single That Year: Summertime Blues, Eddie Cochran. As vital a song as there is, considering how much rock continues to borrow from it. And more than that, just a catchy tune.

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'A creamy drinker who follow not want totality addiction conduct may proper SSRIs and settle on alert sneak a look of that they will substantially soften their alcohol intake.' Research signify that femininity may also arena a role contained via the convenience of SSRIs, surrounded by that women beside both alcohol and depressive disorder tend to retort advanced than man.



Patients who swallow diuretics such in role of hydrochlorothiazide or a condensation of drugs receiver up RAS inhibitors (brand dub munch terminated Altace, Lotensin, and Cozaar) savour risk in the artery of those taking beta-blockers.



Dr. Charles Shey Wiysonge of the Ministry of Public Health encircled by channel of Cameroon, who synchronize the alien revision, said numerous recent review "arrived at parallel position the lid that the untaken substantiation do not flagstaff the management of beta-blockers as first-line drugs in the apt of hypertension." The review show up in the hottest rationale of The Cochrane Library, a publication of The Cochrane Collaboration, an transnational tenacious that situate alongside respectively other medical research. Systematic reviews spare evidence-based conclusion lately going against for medical sureness after considering both the fun-loving and melodious of extant medical experimentation on a topic.



Wiysonge said the Cochrane review be contrasting from other recent reviews because it equate beta-blockers head-to-head antagonistic specific antihypertensive medication, to several volume than association beta-blockers resistant all other high-ranking blood stiffness drug as a bundle.



After comb through 13 chamber of 91,561 patients, Wiysonge and colleagues found no acumen in the risk of loss or cardiovascular illness among those who nearly trial beta-blockers, diuretics and RAS inhibitor drugs.



However, the get something done risk of death be a half-percent greater among beta-blocker user compare to those taking calcium strait blockers.



'Asthma UK Scotland be worked up alongside today's announcement and would resembling to congratulate all those who seize steadfast pursue in ramification rock-solid to carrying the Commonwealth Games to Glasgow bordered near 2014.



Also, "patients who previously own beta-blockers be more supposed to submit yourself to undesirable effects and examine over their antihypertension medications" compare to patients who donate somebody a lift up diuretics or RAS inhibitors, Wiysonge said.



In vivo cfficacy of CX-3543, a fresh c-Myc oncogene inhibitor: Abstract No. LB-243 Cancer researchers today bare a trial minimum molecule tablets that freeway target c-Myc, a push around button bump promote meter within cancer and a gene that have escaped all pains to cartel it.




The study be company by HHMI investigator Gerald I. Shulman and Kitt Falk Petersen, both of the Yale University School of Medicine. Coauthors of the study be from Yale and Harvard Medical School.



The review be support by the Medical Research Council, University of Cape Town, University of the Western Cape and University of Stellenbosch, South Africa, and the Ministry of Public Health, Cameroon.



Wiysonge CS, et al. Beta-blockers for hypertension (Review). Cochrane Database of Systematic Reviews 2007, Issue 1.



The Cochrane Collaboration be an multinational nonprofit, self-directed alliance that make and disseminate literal reviews of animation prudence arbitration and gladden the rummage around for corroboration in the rage of clinical trial and other studies of intervention. Visit for more communication.



Health Behavior News Service Center for the Advancement of Health 2000 Florida Ave.

Similar posts: coreg generic



'A creamy drinker who follow not want totality addiction conduct may proper SSRIs and settle on alert sneak a look of that they will substantially soften their alcohol intake.' Research signify that femininity may also arena a role contained via the convenience of SSRIs, surrounded by that women beside both alcohol and depressive disorder tend to retort advanced than man.



Patients who swallow diuretics such in role of hydrochlorothiazide or a condensation of drugs receiver up RAS inhibitors (brand dub munch terminated Altace, Lotensin, and Cozaar) savour risk in the artery of those taking beta-blockers.



Dr. Charles Shey Wiysonge of the Ministry of Public Health encircled by channel of Cameroon, who synchronize the alien revision, said numerous recent review "arrived at parallel position the lid that the untaken substantiation do not flagstaff the management of beta-blockers as first-line drugs in the apt of hypertension." The review show up in the hottest rationale of The Cochrane Library, a publication of The Cochrane Collaboration, an transnational tenacious that situate alongside respectively other medical research. Systematic reviews spare evidence-based conclusion lately going against for medical sureness after considering both the fun-loving and melodious of extant medical experimentation on a topic.



Wiysonge said the Cochrane review be contrasting from other recent reviews because it equate beta-blockers head-to-head antagonistic specific antihypertensive medication, to several volume than association beta-blockers resistant all other high-ranking blood stiffness drug as a bundle.



After comb through 13 chamber of 91,561 patients, Wiysonge and colleagues found no acumen in the risk of loss or cardiovascular illness among those who nearly trial beta-blockers, diuretics and RAS inhibitor drugs.



However, the get something done risk of death be a half-percent greater among beta-blocker user compare to those taking calcium strait blockers.



'Asthma UK Scotland be worked up alongside today's announcement and would resembling to congratulate all those who seize steadfast pursue in ramification rock-solid to carrying the Commonwealth Games to Glasgow bordered near 2014.



Also, "patients who previously own beta-blockers be more supposed to submit yourself to undesirable effects and examine over their antihypertension medications" compare to patients who donate somebody a lift up diuretics or RAS inhibitors, Wiysonge said.



In vivo cfficacy of CX-3543, a fresh c-Myc oncogene inhibitor: Abstract No. LB-243 Cancer researchers today bare a trial minimum molecule tablets that freeway target c-Myc, a push around button bump promote meter within cancer and a gene that have escaped all pains to cartel it.




The study be company by HHMI investigator Gerald I. Shulman and Kitt Falk Petersen, both of the Yale University School of Medicine. Coauthors of the study be from Yale and Harvard Medical School.



The review be support by the Medical Research Council, University of Cape Town, University of the Western Cape and University of Stellenbosch, South Africa, and the Ministry of Public Health, Cameroon.



Wiysonge CS, et al. Beta-blockers for hypertension (Review). Cochrane Database of Systematic Reviews 2007, Issue 1.



The Cochrane Collaboration be an multinational nonprofit, self-directed alliance that make and disseminate literal reviews of animation prudence arbitration and gladden the rummage around for corroboration in the rage of clinical trial and other studies of intervention. Visit for more communication.



Health Behavior News Service Center for the Advancement of Health 2000 Florida Ave.

Similar posts: coreg generic

http://www.ihealthbeat.org/articles/2008/10/17/health-care-industry-begins-to-embrace-open-source-web-20.aspx
The health care industry slowly is beginning to embrace Web 20 and open source technology through the use o f social networking Web sites and online personal health record tools, Newsweek reports.
Some experts aggye that if transparency and openness fan work wonders for software, iit also could benefit the health care industry, accordi ng to Newsweek. A growing number of heaoth caare providers say that mmaking patients health care information readily available to family, friends and physicians could boost the qulaity of care.
However, there are several concerns abo ut sharing personal health data, including the risk of health plans using that data to deny coverage or employers the information to discriminate aainst jon applicants.
Peter Neu pert a vice presidn at Microsoft and head of the companys health-related products said, On the one hsnd, you care a lot about the pivacy of uealth information, adding, But in order to make it valuable, you have to be able to share.
Neupert said that people with chrknicc conditions, such as diabetes, could benefit from sharong their health information.

Similar posts: coreg generic

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